Primary Biliary Cirrhosis

**Semantic type:** Disease or Syndrome

**Definition:** An autoimmune inflammatory disorder characterized by destruction of the small intrahepatic bile ducts. It affects predominantly females and it may lead to cirrhosis and liver failure. Patients have antimitochondrial and antinuclear antibodies in the peripheral blood.

**Synonyms:** - Chronic Non-Suppurative Destructive Cholangitis - Primary Biliary Cholangitis - Primary Biliary Cholangitis - Primary Biliary Cirrhosis (PBC) - Primary biliary cirrhosis