Histiocytic Sarcoma

**Semantic type:** Neoplastic Process

**Definition:** An aggressive malignant neoplasm with a poor response to therapy, usually presenting as stage III/IV disease. It is characterized by the presence of neoplastic cells with morphologic and immunophenotypic characteristics similar to those seen in mature histiocytes.

**Synonyms:** - Histiocytic sarcoma - Histiocytic sarcoma - SARCOMA, HISTIOCYTIC, MALIGNANT