Lodenosine

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic purine fluoro-dideoxyadenosine derivative, antiviral Lodenosine acts as a reverse transcriptase inhibitor. Although used in clinical trials for treatment of human immunodeficiency (HIV), Lodenosine induces liver or kidney damage and its use has been reconsidered. (NCI04)

**Synonyms:** - 2'-F-dd-ara-A - 2'-FddA - 2'-beta-fluoro-2',3'-dideoxyadenosine - 9-(2,3-Dideoxy-2-fluoro-beta-D-threo-pentofuranosyl) Adenine - DRG-0246 - F-ddA