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C2756Level 5

GM-CSF cDNA/Gold Complex

**Semantic type:** Pharmacologic Substance

**Definition:** Expression vectors containing the complementary DNA (cDNA) of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) coated onto gold particles. A protein cytokine secreted by T-cells and macrophages following cell activation by antigens or mitogens, GM-CSF is indispensable for the growth and development of granulocyte and macrophage progenitor cells. Subsequently, GM-CSF has been shown to activate and stimulate proliferation of mature macrophages and lymphocytes. (NCI04)

**Synonyms:** - GM-CSF cDNA/gold

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