Castleman Disease, Hyaline-Vascular Type

**Semantic type:** Neoplastic Process

**Definition:** The commonest type of Castleman disease. It is seen most commonly in the mediastinum. Histologically this is characterized by hyalinized germinal centers surrounded by small lymphocytes in a concentric fashion, giving an onion skin appearance.

**Synonyms:** - Angiofollicular Lymphoid Hyperplasia, Hyaline-Vascular Type - Castleman's Disease, Hyaline-Vascular Type