pNGVL3-hIL12

**Semantic type:** Pharmacologic Substance

**Definition:** A plasmid vector encoding interleukin-12 (IL-12) with potential use in the gene therapy of cancer. pNGVL3-hIL12 may induce a high level of IL-12 protein expression during transient transfection of host cells. IL-12 is a proinflammatory cytokine with numerous immunoregulatory functions and may augment host immune responses to tumor cells. (NCI04)

**Synonyms:** - pNGVL3-hIL12 (IL-12 DNA)