PR6V10 (ras-12 Asp) Peptide

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor

**Definition:** A truncated synthetic form of the oncogene Ras, whose protein product p21 is located in the plasma membrane and transduces growth and differentiation signals from activated receptors to protein kinases within the cell. Because mutated Ras proteins may represent highly specific epitopes for T-cell recognition, PR6V10 (ras-12 Asp) peptide may be used in the vaccine immunotherapy of cancer. (NCI04)