Verpasep Caltespen

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers. E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes. (NCI04)

**Synonyms:** - BCG65-E7 - Bovine HSP fusion with E7 of HPV16 - HPV 16 E7/HSP65 Vaccine - HPV E7 Peptide Epitope Vaccine - HspE7 - HspE7 - HspE7 Therapeutic Vaccine - SGN-00101 - SGN-00101 - SGN-00101 - VERPASEP CALTESPEN