Tumor Cell Vaccine plus BCG

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A mixture of allogeneic or autologous tumor cells and bacillus Calmette-Guerin (BCG) in a liquid vehicle with potential antineoplastic activity. Vaccination of the host with tumor cell vaccine plus BCG may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor growth. The BCG component serves as an adjuvant, a nonspecific stimulator of the immune response. (NCI04)