Insulin Receptor Substrate 4

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Insulin receptor substrate 4 (1257 aa, ~134 kDa) is encoded by the human IRS4 gene. This protein plays a role in co-localization of receptor tyrosine kinases with SH2 domain-containing downstream signaling proteins.

**Synonyms:** - 160 kDa Phosphotyrosine Protein - IRS-4 - IRS4 - PY160 - Phosphoprotein of 160 kDa - pp160