Pre-Replication Complex

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** The Origin Recognition Complex (ORC) in eukaryotic cells selects genomic sites where pre-replication complexes (pre-RCs) can be assembled. Subsequent activation of these pre-RCs results in bi-directional DNA replication that originates at or close to the ORC DNA binding sites. (From PubMed 12801628)

**Synonyms:** - pre-RC