Pernicious Anemia

**Semantic type:** Disease or Syndrome

**Definition:** Megaloblastic anemia caused by vitamin B-12 deficiency due to impaired absorption. The impaired absorption of vitamin B-12 is secondary to atrophic gastritis and loss of gastric parietal cells.

**Synonyms:** - Intrinsic Factor Deficiency - Vitamin B12 deficiency anemia due to intrinsic factor deficiency - pernicious anemia