Brimodine

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic quinoxaline derivative, Brimodine (brimonidine) acts as a relatively selective alpha-2 adrenergic receptor agonist. Used for open angle glaucoma and eye hypertension, topical administration decreases intraocular pressure with minimal effect on cardiovascular parameters, reducing aqueous humor production and increasing uveoscleral outflow. (NCI04)