Bupivacaine Hydrochloride

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A long-acting, amide-type local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.

**Synonyms:** - BUPIVACAINE HYDROCHLORIDE - Marcain - Marcaine - Marcaine - Sensorcaine - bupivacaine hydrochloride