Azaserine

**Semantic type:** Antibiotic|Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. (NCI04)

**Synonyms:** - AZASERINE - AZASERINE - AZS - CL-337 - CN 15757 - CN-15757 - Cl 337 - Diazoacetate (Ester) L-Serine - Diazoacetate(ester) L-serine - Diazoacetic Acid Ester with Serine - Diazoacetylserine - L-Azaserine - L-Azaserine - L-Diazoacetate(ester) serine - L-diazoacetate (ester) serine - L-serine diazoacetate (ester) - O-diazoacetyl-L-serine - P-165 - P-165 - Serine Diazoacetate - o-Diazoacetyl-L-serine