Chlorzoxazone/Acetaminophen

**Semantic type:** Pharmacologic Substance

**Definition:** Chlorzoxazone Acetaminophen is a combination of muscle relaxant (Chlorzoxazone) and anti-inflammatory analgesic (Acetaminophen) indicated in acute painful musculoskeletal diseases. The active principal metabolite of phenacetin, Acetaminophen appears to inhibit prostaglandin biosynthesis in the central nervous system and less in peripheral tissues. With mild sedative properties, centrally acting Chlorzoxazone inhibits muscle spasm at the spinal cord and subcortical levels of the brain. (NCI04)

**Synonyms:** - Parafon Forte