Carboxyphthalato-1,2-diaminocyclohexaneplatinum

**Semantic type:** Inorganic Chemical|Pharmacologic Substance

**Definition:** A second-generation platinum analog with potential antineoplastic activity. Carboxyphthalato-1,2-diaminocyclohexaneplatinum alkylates DNA at the N-7 position of guanine, thereby producing DNA interstrand crosslinks and DNA strand breaks, and inhibiting DNA replication. (NCI04)

**Synonyms:** - (4-carboxyphthalato)(1,2-diaminocyclohexane)-platinum(II) - (SP-4-3)-Hydrogen (1,2,4-benzenetricarboxylato(3-)-O(1),O(2))(1,2-cyclohexanediamine-N,N') platinate(1-) - 4-CARBOXYPHTHALATOPLATINUM 1R-TRANS-1,2-DIAMINOCYCLOHEXANE COMPLEX - DAC Platinum - DACCP