Dicloxacillin

**Semantic type:** Antibiotic|Organic Chemical|Pharmacologic Substance

**Definition:** A broad-spectrum, semi-synthetic, beta-lactam, penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Dicloxacillin binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis.

**Synonyms:** - 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin - DICLOXACILLIN