Doxycycline Hydrochloride

**Semantic type:** Antibiotic|Organic Chemical|Pharmacologic Substance

**Definition:** The hydrochloride salt form of doxycycline exhibiting antimicrobial activity. Doxycycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. (NCI)

**Synonyms:** - 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)- - Biocamycin - DOXYCYCLINE HYDROCHLORIDE - Deoxy-5-hydroxytetracycline Hydrochloride - Samecin - Tanamicin - Tecacin - Tetradox