Doxycycline Monohydrate

**Semantic type:** Antibiotic|Carbohydrate

**Definition:** The monohydrate form of doxycycline exhibiting antimicrobial activity. Doxycycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. (NCI)