Famotidine

**Semantic type:** Pharmacologic Substance

**Definition:** A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.

**Synonyms:** - FAMOTIDINE - Pepcid - Pepcid AC