Hydroxychloroquine Sulfate

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites (Plasmodium vivax, ovale, and malariae) by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. Hydroxychloroquine also has anti-inflammatory properties and is used in the treatment of rheumatoid arthritis and lupus erythematosus. (NCI04)

**Synonyms:** - HYDROXYCHLOROQUINE SULFATE - Plaquenil