World Of Taxonomy
C29106Level 6

I131-COL1

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A radioimmunoconjugate of a murine monoclonal antibody (MoAb) COL1, labeled with iodine 131 (I-131). COL1 recognizes an epitope of carcinoembryonic antigen (CEA), which is over-expressed in many tumor cell types. I-131 MoAb COL1 delivers beta and gamma radiation emitting I-131 nuclide directly to tumor cells that express CEA, thereby allowing imaging and/or treatment of cancers.

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