Burkitt Lymphoma

**Semantic type:** Neoplastic Process

**Definition:** A highly aggressive lymphoma composed of monomorphic medium-sized B-cells with basophilic cytoplasm and numerous mitotic figures. It is often associated with the presence of Epstein-Barr virus (EBV) and is commonly seen in AIDS patients. Three morphologic variants are recognized: classical Burkitt lymphoma, Burkitt lymphoma with plasmacytoid differentiation, and atypical Burkitt/Burkitt-like lymphoma. All cases express the MYC translocation [t(8;14)]. (WHO, 2001)

**Synonyms:** - Burkitt lymphoma, unspecified site - Burkitt's Lymphoma - Burkitt's lymphoma - NHL, Burkitt lymphoma (BL) - Small Non-Cleaved Cell Lymphoma, Burkitt's Type