Lodoxamide Tromethamine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity. Upon administration to the eye, lodoxamide tromethamide inhibits type I immediate hypersensitivity reaction by preventing the antigen-stimulated calcium influx into mast cells, thereby inhibiting release of histamine. Lodoxamide tromethamide also prevents the release of slow-reacting substances of anaphylaxis (SRS-A) and inhibits eosinophil chemotaxis.

**Synonyms:** - Alomide - LODOXAMIDE TROMETHAMINE