Melanoma Monoclonal Antibody hIgG2A

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** One of a number human monoclonal antibodies of the immunoglobulin subclass IgG2a directed against melanoma antigens with potential antineoplastic activity. A melanoma monoclonal antibody, subclass IgG2A, may have potential use as a diagnostic agent and, therapeutically, may induce macrophage-mediated cytotoxicity against antibody-bound melanoma cells. (NCI04)

**Synonyms:** - M A IG2A Human Melanoma