Monoclonal Antibody 9.2.27 F(ab)

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** The Fab fragment of the 9.2.27 monoclonal antibody. 9.2.27 monoclonal antibody recognizes the high-molecular-weight melanoma-associated antigen (HMW-MAA), an antigen expressed on a majority of melanomas. Monoclonal antibody 9.2.27 FAB binds with high affinity to melanoma cells and has potential use in immunodiagnostic imaging and the immunotherapy of melanoma. Monoclonal antibody 9.2.27 FAB exhibits improved tumor localization and a shorter half-life than the complete antibody. (NCI04)

**Synonyms:** - 9.2.27 FAB - MOAB 9.2.27 FAB