MOAB B-3-CHX-A-DTPA

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A monoclonal antibody B3, recognizing the tumor-associated Lewis Y antigen, is conjugated to a backbone-substituted derivative of DTPA, 2-(p-isothiocyanatobenzyl)-cyclohexyl-diethylenetriaminepentaacetic acid (CHX-A DTPA). DTPA is a bifunctional chelating agent thereby allowing for the binding of radioisotopes to the immunoconjugate.