Monoclonal Antibody B6.2 F(ab')

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** The Fab fragment of the B6.2 monoclonal antibody that recognizes the B6.2 antigen, a 90,000-d glycoprotein found on the surface of human mammary tumors. MOAB B6.2 F (AB') binds to breast carcinoma cells and has potential use in immunodiagnostic imaging and the immunotherapy of breast cancer. MOAB B6.2 F (AB') exhibits improved tumor localization and a shorter half-life than the complete antibody. (NCI04)