Monoclonal Antibody IMMU-14

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** An anti-carcinoembryonic antigen (anti-CEA) murine monoclonal immunoglobulin G (IgG) with potential antineoplastic activity. CEA is overexpressed in several cancer cell types, including gastrointestinal, breast, and non-small cell lung cancers. MOAB IMMU-14 can be conjugated with a radioactive element for use in radioimmunotherapy (RIT), a regimen that uses a tumor-specific monoclonal antibody to deliver targeted radiation to cancer cells. (NCI04)

**Synonyms:** - MOAB IMMU-14