Omalizumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor. (NCI04)

**Synonyms:** - Anti-IgE Monoclonal Antibody E25 - IGE 025 - OMALIZUMAB - Olizumab - Xolair - rhuMAb-E25