Propoxyphene Napsylate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic diphenyl propionate derivative structurally related to methadone, Propoxyphene Napsylate acts as a central narcotic and analgesic agent by interaction with mu opioid receptors, but with less selectivity then morphine. The dextro-isomer has analgesic effect, while the levo-isomer exerts an antitussive effect. The napsylate salt allows better dosage formulation than the hydrochloride salt. (NCI04)

**Synonyms:** - Darvon-N - PROPOXYPHENE NAPSYLATE