Murine MCA Ricin Conjugate

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** An immunotoxin consisting of a murine monoclonal antibody (MCA) conjugated to the toxin ricin. The monoclonal antibody component binds to cell surface antigens, thereby targeting delivery of cytotoxic ricin to a specific cell type. The ricin component binds to cells and disrupts ribosomal activity and protein synthesis and induces cell cycle arrest. (NCI04)

**Synonyms:** - Ricin Conjug. Murine MCA