mRNA Surveillance

**Semantic type:** Molecular Function

**Definition:** mRNA Surveillance works within elaborate cellular mechanisms to ensure accurate gene expression by assessing suitable mRNA quality for translation and prevents the synthesis of truncated or aberrant proteins. By nonsense-mediated decay, mRNA surveillance facilitates the detection and destruction of mRNAs that contain premature termination codons. Also, by nonstop decay, mRNA surveillance depletes mRNAs that lack in-frame termination codons.