Yttrium 90 Monoclonal Antibody T101

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A murine monoclonal antibody directed against the CD5 antigen and labeled with Yttrium-90, a beta-emitting radioisotope. CD5 is a type-I transmembrane glycoprotein found on thymocytes, T-cells and a subset of B-cells. Yttrium 90 monoclonal antibody T101 may bind to and selectively irradiate and kill CD5-positive tumor cells. Yttrium 90 has a half-life of 2.5 days and can be administered on an outpatient basis. (NCI04)

**Synonyms:** - MOAB YT-90 T101