1,2-Dimethylhydrazine Dihydrochloride

**Semantic type:** Hazardous or Poisonous Substance

**Definition:** The chloride salt of a compound used experimentally to induce tumors in animal models of carcinogenesis. In mice and rats, 1,2-dimethylhydrazine may induce carcinogenesis through deregulation of the cell cycle. This agent primarily induces gastrointestinal and vascular tumors. 1,2-Dimethylhydrazine may be found in small amounts in the environment due to its use in industry and agriculture. (NCI04)

**Synonyms:** - 1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE