2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine

**Semantic type:** Hazardous or Poisonous Substance

**Definition:** A synthetic, gray-white crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). It is one of the most abundant heterocyclic amines in a typical Western diet. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05)

**Synonyms:** - 1-methyl-6-phenyl-1h-imidazo(4,5-b)pyridin-2-amine - 2-AMINO-1-METHYL-6-PHENYLIMIDAZO(4,5-B)PYRIDINE - PHIP - PhIP