N-ethyl-N'-nitro-N-nitrosoguanidine

**Semantic type:** Hazardous or Poisonous Substance

**Definition:** An alkyl nitrosoguanidine with carcinogenic properties. Used to induce cancer in experimental animal models, N-ethyl-N'-nitro-N-nitrosoguanidine ethylates DNA, resulting in single- and double-stranded DNA breaks and the inhibition of DNA replication. (NCI04)

**Synonyms:** - ENNG - N-ETHYL-N'-NITRO-N-NITROSOGUANIDINE