Bence Jones Protein

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor

**Definition:** Human immunoglobulin kappa and/or lambda light chains detected in their free form in serum or urine samples as a result of overproduction by plasma cells due to neoplastic proliferation. Detection of immunoglobulin light chains in concentrations that exceed that of heavy chains is associated with plasma cell neoplasms.

**Synonyms:** - Bence Jones protein - Bence-Jones Protein