E3 SUMO-Protein Ligase PIAS3

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 SUMO-protein ligase PIAS3 (628 aa, ~68 kDa) is encoded by the human PIAS3 gene. This protein plays a role in the regulation of protein sumoylation and in the inhibition of signal transducer and activator of transcription 3 transcription factor activity.

**Synonyms:** - E3 SUMO-protein transferase PIAS3 - EC 2.3.2.- - EC 6.3.2.-, Formerly - PIAS3 - Protein Inhibitor of Activated STAT Protein 3 - Protein Inhibitor of Activated STAT3