Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Isoform

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (1068 aa, ~124 kDa) is encoded by the human PIK3CA gene. This protein plays a role in signaling pathways underlying the regulation of apoptosis, cell growth, and angiogenesis.

**Synonyms:** - EC 2.7.1.153 - EC 2.7.11.1 - PI3-Kinase P110 Subunit Alpha - PI3-Kinase Subunit Alpha - PI3K - PI3K-Alpha - PI3Kalpha - PIK3CA - Phosphatidylinositol 3-Kinase, Catalytic, 110-kD, Alpha - Phosphatidylinositol 3-Kinase, Catalytic, Alpha - Phosphatidylinositol 4,5-Bisphosphate 3-Kinase 110 kDa Catalytic Subunit Alpha - Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit, Alpha Isoform - Phosphoinositide-3-Kinase Catalytic Alpha Polypeptide - PtdIns-3-Kinase Subunit Alpha - PtdIns-3-Kinase Subunit p110-Alpha - PtdIns-3-Kinase p110 - Serine/Threonine Protein Kinase PIK3CA - p110-Alpha - p110alpha