Ganglioneuroma

**Semantic type:** Neoplastic Process

**Definition:** A benign neuroblastic tumor of the sympathetic nervous system that occurs in childhood. Ganglioneuroma typically arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. Common presenting features include a palpable abdominal mass, hepatomegaly, and a thoracic mass detected on routine chest X-ray.

**Synonyms:** - GANGLIONEUROMA, BENIGN - Ganglioneuroma (Schwannian Stroma-Dominant) - Neural Crest Tumor, Benign