Cowden Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal dominant hereditary syndrome characterized by a variety of hamartomas and neoplasms including verrucous skin lesions, fibromas of the oral cavity, facial trichilemmomas, hamartomatous colonic polyps, thyroid neoplasms, breast cancer, and dysplastic gangliocytomas of the cerebellum.

**Synonyms:** - Cowden Disease - Cowden disease - Cowden syndrome - Cowden's Disease - multiple hamartoma syndrome