Leiomyosarcoma

**Semantic type:** Neoplastic Process

**Definition:** An aggressive malignant mesenchymal neoplasm that arises from smooth muscle cells and is characterized by a proliferation of neoplastic spindle cells. Morphologic variants include epithelioid, granular cell, inflammatory, and myxoid leiomyosarcoma. It usually occurs in post-menopausal women.

**Synonyms:** - LEIOMYOSARCOMA, MALIGNANT - Leiomyosarcoma (excluding uterine leiomyosarcoma) - Leiomyosarcoma - not uterine - Leiomyosarcoma, NOS - Leiomyosarcomas - Malignant Smooth Muscle Neoplasm - Malignant Smooth Muscle Tumor - leiomyosarcoma