Broxuridine

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** A halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks.

**Synonyms:** - 5-BrdU - 5-Bromo-2'-deoxyuridine - 5-Bromo-2'-deoxyuridine - 5-Bromodeoxyuridine - 5-Bromodeoxyuridine - 5-Bromouracil Deoxyriboside - 5-Bromouracil deoxyriboside - 5-Bromouracil-2-deoxyriboside - 5-Bromouracil-2-deoxyriboside - 5-Budr - BRDU - BROXURIDINE - BrdU - Bromo Deoxyuridine - Bromodeoxyuridine - Bromodeoxyuridine - Bromouracil Deoxyriboside - Bromouracil deoxyriboside - Bromouridine - Broxine - Neomark - Neomark-BU - broxuridine