Multiple Myeloma

**Semantic type:** Neoplastic Process

**Definition:** A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

**Synonyms:** - Kahler disease - MYELOMA, PLASMA CELL, MALIGNANT - Multiple Myeloma/Plasma Cell Myeloma - Multiple Myeloma/Plasma Cell Myeloma - Multiple myeloma - Myeloma - Myeloma - Myeloma, NOS - Myeloma, NOS - Myelomatosis - Plasma Cell Myeloma - Plasma Cell Myeloma - Plasma Cell Myeloma - Plasma Cell Myeloma - Plasma Cell Myeloma - Plasma Cell Myeloma - Plasma Cell Myeloma/Multiple Myeloma - Plasma cell myeloma - multiple myeloma - myeloma - myelomatosis - plasma cell myeloma