Liver Acinus Zone 1

**Semantic type:** Anatomical Structure

**Definition:** An area of hepatocytes that are closest to an arteriole. Because of their close proximity to oxygenated blood, the cells in this zone carry out oxidative processes such as beta-oxidation, cholesterol synthesis and gluconeogenesis.

**Synonyms:** - Periportal Zone - Zone 1 - Zone 1 of Liver Acinus - Zone 1 of the Liver Acinus