Capsaicin

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A chili pepper extract with analgesic properties. Capsaicin is a neuropeptide releasing agent selective for primary sensory peripheral neurons. Used topically, capsaicin aids in controlling peripheral nerve pain. This agent has been used experimentally to manipulate substance P and other tachykinins. In addition, capsaicin may be useful in controlling chemotherapy- and radiotherapy-induced mucositis.

**Synonyms:** - (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide - (E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide - CAPSAICIN - N-(4-hydroxy-3-methoxyphenylmethyl) -8-Methyl-6-Nonenamide - capsaicin