C3447Level 5
Werner Syndrome
**Semantic type:** Disease or Syndrome
**Definition:** A rare, autosomal recessive syndrome caused by mutations in the WRN gene. It is characterized by the appearance of accelerated aging following puberty. It is associated with the development of diabetes mellitus, atherosclerosis, cataracts, and cancer.
**Synonyms:** - Adult Progeria - WS - WS - Werner syndrome - Werner's Syndrome - adult progeria
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