Wolfram Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** A rare inherited syndrome caused by mutations in the WFS1 and CISD2 genes. It is characterized by diabetes insipidus, diabetes mellitus, optic atrophy, and deafness.

**Synonyms:** - DIDMOAD - DIDMOAD - Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness Syndrome